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Home Q&A

What drug class is hydroxyzine?

August 14, 2022
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Hydroxyzine is in a class of medications called antihistamines. It works by blocking the action of histamine a substance in the body that causes allergic symptoms.

Is hydroxyzine the same thing as Xanax?

Hydroxyzine and Xanax belong to different drug classes. Hydroxyzine is an antihistamine with anticholinergic (drying) and sedative properties and Xanax is an anti-anxiety medication in the benzodiazepine class. A brand name for hydroxyzine is Vistaril.

Is hydroxyzine good for anxiety?

Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery.

Is hydroxyzine like a benzo?

No, these drugs are not the same, but sometimes people confuse them. Both are available by prescription only, but hydroxyzine is an antihistamine medication used to treat allergic reactions and anxiety. Xanax is also used to treat anxiety, but it is classified as a benzodiazepine drug.

Can you fail a drug test for hydroxyzine?

Other ringed xenobiotics like carbamazepine, cyproheptadine, cyclobenzaprine, and quetiapine have been reported to cause false positives. Likewise, structurally similar agents like diphendyramine, hydroxyzine, cetirizine can also cause false positive TCA screens.

What are the dangers of hydroxyzine?

  • Chest pain or discomfort.
  • difficulty with swallowing.
  • fast heartbeat.
  • hives, itching, or skin rash.
  • irregular or slow heart rate.
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.
  • shortness of breath.

Is hydroxyzine stronger than Xanax?

The authors were able to determine that alprazolam was more effective than hydroxyzine for pre-surgery anxiety. While there are no available studies directly comparing these two medications for anxiety disorders, there is a study that compared hydroxyzine to a different benzodiazepine — bromazepam — in people with GAD.

Which is better for anxiety Xanax or hydroxyzine?

The two drugs were comparable in regards to effects in somnolence and memory, but the effects of hydroxyzine lead to a more pronounced decrease in blood pressure. While they are both effective pre-procedural drugs, Xanax may be preferred due to its more pronounced effect on anxiety and adverse event profile.

Is hydroxyzine habit forming?

Hydroxyzine is not a controlled substance, is non-habit forming and does not cause dependence or withdrawal symptoms. It is a good choice for patients with mild anxiety symptoms and those who do not want to take a daily medication or a federally controlled substance (Source).

Can I take hydroxyzine every night?

The recommended dose for hydroxyzine for sleep varies, depending on age and reaction to the medication. For adults, however, the typical hydroxyzine dosage for sleep range is 25 mg to 100 mg, taken before bed, either with or without food. If you use hydroxyzine for sleep, take it as your doctor has prescribed.

How long does it take hydroxyzine to wear off?

Hydroxyzine’s half-life is about 14 hours. So it takes about 14 hours for your body to get rid of half of a dose of hydroxyzine. Typically, it takes about five half-lives for a drug to completely leave your system. For hydroxyzine, this means the drug will stay in your system for about 70 hours after your last dose.

What can you not take with hydroxyzine?

Certain medications (e.g., sotalol, quinidine, thioridazine, chlorpromazine, droperidol, pimozide, moxifloxacin, mefloquine, pentamidine, arsenic trioxide, probucol, tacrolimus) can increase the risk of a type of abnormal heart rhythm called QT prolongation and should not be used in combination with hydroxyzine.

Is hydroxyzine fast acting for anxiety?

Hydroxyzine starts working very quickly. Most people will start to feel it kick in within 30 minutes and will feel its maximum effect at around 2 hours.

Does hydroxyzine work for panic attacks?

As reported in our case, an acute exacerbation of panic disorder was effectively managed by hydroxyzine in a healthy adult. If practitioners recognize this association, extensive use of benzodiazepines may be prevented.

How long does hydroxyzine last for anxiety?

How long does hydroxyzine last for anxiety? The effects of hydroxyzine typically last 3 to 4 hours.

Can hydroxyzine be used for depression?

Significant sedation has limited hydroxyzine use in clinical practice. Another disadvantage is that hydroxyzine is not effective for depression, a commonly associated disorder in GAD.

Will hydroxyzine show up on a 12 panel drug test?

Hydroxyzine is not known to cause false-positives for benzodiazepines on urine drug tests. However, it has been reported to cause false-positives for another class of drugs, tricyclic antidepressants.

Is 25mg of hydroxyzine strong?

The recommended dose of Vistaril for treating itch (pruritus) is 25 mg, 3 or 4 times daily. For sedation, the recommended dose is 50 to 100 mg. The dose to treat anxiety and tension is 50 to 100 mg 4 times daily.

Is hydroxyzine a muscle relaxer?

Hydroxyzine has demonstrated bronchodilator activity (opening up of the airways); antihistaminic (relieves symptoms of allergy including itch), antiemetic (relieves nausea and vomiting), and analgesic (pain-relieving) effects; as well as skeletal muscle relaxation.

How much hydroxyzine do I take to sleep?

The correct dosage for taking Hydroxyzine (Atarax, Vistaril) can be determined by your doctor. To help improve sleep, adults should take 50-100 mg daily. This medication can be taken with or without food.

Which hydroxyzine is better for anxiety?

Hydroxyzine is available in two different salt forms, hydroxyzine hydrochloride (HCl) (commonly known as Atarax) and hydroxyzine pamoate (commonly known as Vistaril). It’s often believed that Atarax is better for treating itching and Vistaril is better for treating anxiety or difficulty sleeping.

Is hydroxyzine an SSRI?

While hydroxyzine is an antihistamine, it is also a serotonin antagonist. In other words, taking hydroxyzine or Vistaril for anxiety works similarly to taking SSRIs—another type of medication used to treat anxiety—by making more serotonin available in your brain.

Is hydroxyzine the same as Benadryl?

Generally speaking, hydroxyzine is an antihistamine related to over-the-counter (OTC) medications like Benadryl and Zyrtec that are used to treat symptoms of allergies and colds such as runny nose and itchy or watery eyes.

What drugs should not be taken with hydroxyzine?

Certain medications (e.g., sotalol, quinidine, thioridazine, chlorpromazine, droperidol, pimozide, moxifloxacin, mefloquine, pentamidine, arsenic trioxide, probucol, tacrolimus) can increase the risk of a type of abnormal heart rhythm called QT prolongation and should not be used in combination with hydroxyzine.

Can hydroxyzine worsen anxiety?

One study also suggests cetirizine and hydroxyzine have a greater chance of causing anxiety and mood changes than other antihistamines. Hydroxyzine can also be used to treat anxiety conditions. So if you notice your symptoms worsen after starting this medication, contact your provider to discuss it further.

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