Synonyms: chromatophilic substance. Nissl bodies, also called nissl substance, are granules in the cytoplasm of nerve cell bodies that are strongly stained by basic dyes and appear as basophilic clumps on light microscopy. They consist of aggregates of free polyribosomes and rough endoplasmic reticulum.
What is Chromatophilic substance made of?
What is a chromatophilic Substance? free and bound ribosomes producing proteins, also called Nissl bodies.
Where is Chromatophilic substance found?
Answer and Explanation: Chromatophilic substance, also known as Nissl substance, is found in neurons. It is highly basophilic. Chromatophilic substance is composed of rough endoplasmic reticulum.
What is the Nissl substance?
Nissl substance is a reticulum of channels within neurons. Its external membranes are studded with rows, loops, and spirals of ribosomes, although some regions are smooth. Ribosomes also lie free in the cytoplasm as polysomal rosettes between cisternae.
Where is Nissl substance found?
Subcellular structures found in nerve cell bodies and DENDRITES. They consist of granular endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH) and RIBOSOMES.
What causes Chromatolysis?
Chromatolysis is the dissolution of the Nissl bodies in the cell body of a neuron. It is an induced response of the cell usually triggered by axotomy, ischemia, toxicity to the cell, cell exhaustion, virus infections, and hibernation in lower vertebrates.
What is Endoneurial?
: the delicate connective tissue network holding together the individual fibers of a nerve trunk.
What is a synapse?
Synapses are part of the circuit that connects sensory organs, like those that detect pain or touch, in the peripheral nervous system to the brain. Synapses connect neurons in the brain to neurons in the rest of the body and from those neurons to the muscles.
What are Nissl bodies and their functions?
The functions of Nissl bodies are thought to be the same as those of the rough endoplasmic reticulum in general, primarily the synthesis and segregation of proteins. Similar to the ergastoplasm of glandular cells, Nissl bodies are the main site of protein synthesis in the neuronal cytoplasm.
What is true of mixed nerve?
What is true of a mixed nerve? It contains only afferent nerve fibers. It contains both afferent and efferent nerve fibers.
What is Telodendria in neuron?
Telodendria (transmissive) – the terminal branches of an axon; make contact with other neurons at synapses.
What is the function of Nissl Chromatophilic bodies?
What is the function of Nissl (chromatophilic) bodies? They continually renew cell membranes and proteins of the cytosol.
What is the function of Nissl granules?
Nissl’s Granules are the substances found in the neurons which are a large granular type of body. These granules are very useful for protein synthesis also help to transport these proteins to the part known as cyton.
What are Nissl’s granules made of?
A Nissl body, also known as Nissl substance and Nissl material, is a large granular body found in neurons. These granules are of rough endoplasmic reticulum (RER) with rosettes of free ribosomes, and are the site of protein synthesis.
How does the Nissl substance appear and what is it in reality?
Under the light microscope, nissl substances range in appearance from rhomboid blocks in large neurons to particulate materials in the cell bodies of smaller neurons. Nissl bodies are nodal points in the endoplasmic reticulum, which permeate the cell body and dendrites.
Is chromatolysis reversible?
Chromatolysis is also reversible in CNS neurons.
What is meant by chromatolysis?
Definition of chromatolysis
: the dissolution and breaking up of chromophil material (such as chromatin) of a cell and especially a nerve cell.
Where is neurofilament located?
Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter and many micrometers in length.
Are nerves made of collagen?
In the central nervous system, collagen is present only in the meninges and vasculature. On the contrary, the peripheral nervous system contains sub- stantial amounts of collagen which effect the function of the nerve (Mei Liu 1988).
What is the Axonotmesis?
Axonotmesis is a term that describes the range of PNIs that are more severe than a minor insult, such as those resulting in neurapraxia, yet less severe than the transection of the nerve, as observed in neurotmesis.
What are nerve bundles called?
Each bundle of nerve fibers is called a fasciculus and is surrounded by a layer of connective tissue called the perineurium. Within the fasciculus, each individual nerve fiber, with its myelin and neurilemma, is surrounded by connective tissue called the endoneurium.
What is hematopoiesis quizlet?
Define: Hematopoiesis. – a continuous, regulated process of blood cell production that includes cell renewal, proliferation, differentiation, and maturation. – results in the formation, development, and specialization of all functional blood cells.
What are the most abundant Agranulocytes?
Monocytes and lymphocytes are agranulocytes. Neutrophils, the most numerous leukocytes, are phagocytic and have light-colored granules. Eosinophils have granules and help counteract the effects of histamine. Basophils secrete histomine and heparin and have blue granules.
What plasma protein is essential to platelet adhesion quizlet?
Fibrinogen one of the 3 main plasma proteins in the blood creates bridges between aggregating platelets. The receptors (binding sites) for fibrinogen on the platelet plasma membrane become exposed and activated during platelet activation.